Recombinant Human PAX8 Protein, C-Myc/DDK-Tagged

• Cat.No.: PAX8-01H
• Product Overview: Recombinant Human PAX8 Protein, C-Myc/DDK-Tagged was expressed in HEK293T cell.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
• Molecular Mass: 34.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80°C.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Cytogenetics: 2q14.1
• Refseq Size: 3755
• Refseq ORF: 963
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: PAX8 paired box 8 [ Homo sapiens (human) ]
• Official Symbol: PAX8
• Synonyms: OTTHUMP00000158659; OTTHUMP00000158660; paired box 8; paired domain gene 8
• Gene ID: 7849
• mRNA Refseq: NM_013953.4
• Protein Refseq: NP_039247.1
• MIM: 167415
• UniProt ID: Q06710