Recombinant Human NT5C Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NT5C-6577H
• Product Overview: NT5C MS Standard C13 and N15-labeled recombinant protein (NP_055410) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene.
• Molecular Mass: 23.4 kDa
• AA Sequence: MARSVRVLVDMDGVLADFEAGLLRGFRRRFPEEPHVPLEQRRGFLAREQYRALRPDLADKVASVYEAPGFFLDLEPIPGALDAVREMNDLPDTQVFICTSPLLKYHHCVGEKYRWVEQHLGPQFVERIILTRDKTVVLGDLLIDDKDTVRGQEETPSWEHILFTCCHNRHLVLPPTRRRLLSWSDNWREILDSKRGAAQRETRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NT5C 5', 3'-nucleotidase, cytosolic [ Homo sapiens (human) ]
• Official Symbol: NT5C
• Synonyms: NT5C; 5, 3-nucleotidase, cytosolic; 5 nucleotidase, deoxy (pyrimidine), cytosolic type C, UMPH2, uridine 5 prime monophosphate hydrolase 2; 5(3)-deoxyribonucleotidase, cytosolic type; cdN; DNT 1; dNT 1; DNT1; PN I; deoxy-5-nucleotidase 1; cytosolic 5,3-pyrimidine nucleotidase; uridine 5-prime monophosphate hydrolase 2; uridine 5-monophosphate phosphohydrolase 2; 5 nucleotidase, deoxy (pyrimidine), cytosolic type C; DNT; P5N2; PN-I; PN-II; UMPH2; dNT-1
• Gene ID: 30833
• mRNA Refseq: NM_014595
• Protein Refseq: NP_055410
• MIM: 191720
• UniProt ID: Q8TCD5