NT5C
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Official Full Name
5, 3-nucleotidase, cytosolic -
Overview
This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5 deoxyribonucleotides (dNTP) and 2(3)-dNTP and ribonucleotides, but not 5 ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. -
Synonyms
NT5C;5, 3-nucleotidase, cytosolic;5 nucleotidase, deoxy (pyrimidine), cytosolic type C , UMPH2, uridine 5 prime monophosphate hydrolase 2;5(3)-deoxyribonucleotidase, cytosolic type;cdN;DNT 1;DNT1;PN I;deoxy-5-nucleotidase 1;cytosolic 5,3-
Recombinant Proteins
- Human
- Mouse
- E.coli
- HEK293
- Mammalian Cells
- Yeast
- GST
- His&T7
- Non
- His&Fc&Avi
- His
- Flag
- Myc&DDK
- His&Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NT5C-1380H | Recombinant Human NT5C, GST-tagged | E.coli | Human | GST | 1-201aa | |
| NT5C-1074H | Recombinant Human NT5C protein, His & T7-tagged | E.coli | Human | His&T7 | Asp12~Leu200 |
|
| NT5C-1225HCL | Recombinant Human NT5C cell lysate | Human | Non |
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| NT5C-1554H | Recombinant Human NT5C Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| NT5C-1554H-B | Recombinant Human NT5C Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| Nt5c-1865M | Recombinant Mouse Nt5c Protein, His-tagged | E.coli | Mouse | His | Asp12-Leu200 |
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| NT5C-2153HFL | Recombinant Full Length Human NT5C Protein, C-Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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| NT5C-3533H | Recombinant Human NT5C protein, His-tagged | Yeast | Human | His | 1-201aa |
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| Nt5c-4513M | Recombinant Mouse Nt5c Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| NT5C-4633H | Recombinant Human NT5C protein, His&Myc-tagged | E.coli | Human | His&Myc | 1-201a.a. |
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| NT5C-6577H | Recombinant Human NT5C Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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Involved Pathway
NT5C involved in several pathways and played different roles in them. We selected most pathways NT5C participated on our site, such as Purine metabolism,Pyrimidine metabolism,Nicotinate and nicotinamide metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NT5C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | UCKL1,NANP,DNMT3A,IDI1,GCSHA,G6PC3,PGAM1A,GNPDA2,AZIN2,NOS2A |
| Nicotinate and nicotinamide metabolism | NADKA,AOX1,NMNAT3,PNP5A,BST1,NT5C1B,QPRT,NT5C2,NUDT12,NADKB |
| Purine metabolism | POLR2K,ATIC,POLR3D,PRPS1,POLD1,TWISTNB,CECR1,IMPDH1,ITPA,ADAL |
| Pyrimidine metabolism | NT5C2A,CANT1B,UPP2,UPB1,POLR2E,POLR2J3,POLR2J,NUDT2,NT5C3A,POLR2F |
Protein Function
NT5C has several biochemical functions, for example, 5-nucleotidase activity,metal ion binding,nucleotidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NT5C itself. We selected most functions NT5C had, and list some proteins which have the same functions with NT5C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 5-nucleotidase activity | NT5C3L,ACPP,NT5DC3,NT5C1B,NT5C2A,NT5M,NT5DC2,NT5C1A,NT5C1BA,NT5C2 |
| metal ion binding | COL27A1,MPO,PKMYT1,EXT1A,KLF5,ZFP36,CMTM2A,HNRNPA0L,ZNF280A,ZFP821 |
| nucleotidase activity | NT5M |
Interacting Protein
NT5C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NT5C here. Most of them are supplied by our site. Hope this information will be useful for your research of NT5C.
TNS2;2_aha_camp
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