Recombinant Human MYL12B Protein, MYC/DDK-tagged

• Cat.No.: MYL12B-2277H
• Product Overview: Recombinant human MYL12B protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM, Mar 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 19.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MYL12B myosin, light chain 12B, regulatory [ Homo sapiens ]
• Official Symbol: MYL12B
• Synonyms: MLC-B; MRLC2
• Gene ID: 103910
• mRNA Refseq: NM_001144944
• Protein Refseq: NP_001138416
• MIM: 609211
• UniProt ID: O14950