Recombinant Human LTA, His-tagged

• Cat.No.: LTA-31534TH
• Product Overview: RecombinantHumanTNF-beta, expressed in (BTI-Tn-5B1-4) High-5 Insect Cells. This is an 18.6 kDa protein containing 172 amino acid residues. (Due to glycosylation, TNF-beta has an approximate molecular weight of 19.3 kDa.)

Specification

• Species: Human
• Tag: His
• Description: The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis.
• Conjugation: HIS
• Form: Lyophilised:Centrifuge the vial prior to opening.Reconstitute in water to a concentration of °C for 1 week or -20°C for future use.
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneEndotoxin level is less than 0.1 ng per μg (1EU/μg).
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Sequences of amino acids: GVGLTPSAAQ TARQHPKMHL AHSTLKPAAH LIGDPSKQNS LLWRANTDRA FLQDGFSLSN NSLLVPTSGI YFVYSQVVFS GKAYSPKATS SPLYLAHEVQ LFSSQYPFHV PLLSSQKMVY PGLQEPWLHS MYHGAAFQLT QGDQLSTHTD GIPHLVLSPS TVFFGAFAL
• Sequence Similarities: Belongs to the tumor necrosis factor family.

Gene Information

• Gene Name: LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ]
• Official Symbol: LTA
• Synonyms: LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1
• Gene ID: 4049
• mRNA Refseq: NM_000595
• Protein Refseq: NP_000586
• MIM: 153440
• Uniprot ID: P01374
• Chromosome Location: 6p21.3
• Pathway: Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem
• Function: cytokine activity; receptor binding; tumor necrosis factor receptor binding