Recombinant Human LGALS4 protein, His-tagged

• Cat.No.: LGALS4-323H
• Product Overview: Recombinant Human LGALS4 protein (Met1-Ile323), fused to His tag at N-terminus, was expressed in human 293 cells (HEK293).

Specification

• Description: Galectin-4 (Gal-4), also known as L36LBP (L-36 lactose-binding protein). The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer.
• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized from 0.22 um filtered solution in 50 mM HEPES, 150 mM NaCl, pH7.5. Normally sucrose is added as protectant before lyophilization.
• Molecular Mass: The protein has a calculated MW of 38.1 kDa. The protein migrates as 40-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Protein length: 323
• Endotoxin: Less than 1.0 EU per ug by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 centigrade to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: LGALS4
• Official Symbol: LGALS4
• Synonyms: LGALS4; lectin, galactoside-binding, soluble, 4; galectin-4; GAL4; galectin 4; gal-4; antigen NY-CO-27; lactose-binding lectin 4; L-36 lactose-binding protein; L36LBP
• Gene ID: 3960
• mRNA Refseq: NM_006149
• Protein Refseq: NP_006140
• MIM: 602518
• UniProt ID: P56470