Recombinant Human INTS6 Protein, His-tagged

• Cat.No.: INTS6-481H
• Product Overview: Recombinant Human INTS6, transcript variant 3, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by tHis gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, tHis gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for tHis gene.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 12.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: INTS6 integrator complex subunit 6 [ Homo sapiens ]
• Official Symbol: INTS6
• Synonyms: INTS6; integrator complex subunit 6; DDX26, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26; DBI 1; DDX26A; DICE1; HDB; INT6; Notchl2; DEAD box protein; RNA helicase HDB; protein deleted in cancer 1; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26; DBI-1; DDX26; DKFZp434B105
• Gene ID: 26512
• mRNA Refseq: NM_001039937
• Protein Refseq: NP_001035026
• MIM: 604331
• UniProt ID: Q9UL03