Recombinant Human GABRB3 Protein (M1-F332, SQPARAA, A447-N473 end), C-StrepII-tagged

• Cat.No.: GABRB3-05H
• Product Overview: Recombinant human GABRB3(M1-F332)-(SQPARAA)-(A447-N473 end)-twin-StrepII was expressed in mammalian cells.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: Strep II
• Protein Length: M1-F332, SQPARAA, A447-N473 end
• Description: This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described.
• Form: Liquid
• Endotoxin: < 0.01 EU/μg of the protein
• Purity: 80%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.005% (w/v) GDN, 0.0005% (w/v) CHS
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 [ Homo sapiens (human) ]
• Official Symbol: GABRB3
• Synonyms: GABRB3; gamma-aminobutyric acid (GABA) A receptor, beta 3; gamma-aminobutyric acid receptor subunit beta-3; GABA(A) receptor; beta 3; GABA(A) receptor, beta 3; GABAA receptor beta-3 subunit; GABA(A) receptor beta-3 subunit; GABA-alpha receptor beta-2 subunit; ECA5; MGC9051
• Gene ID: 2562
• mRNA Refseq: NM_000814
• Protein Refseq: NP_000805
• MIM: 137192
• UniProt ID: P28472