Recombinant Human Eukaryotic Translation Initiation Factor 2 Alpha Kinase 4, GST-tagged
Cat.No. : | EIF2AK4-1011H |
Product Overview : | Recombinant human EIF2AK4 (192-1024) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
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Species : | Human |
Source : | Sf9 Cells |
Tag : | GST |
Protein Length : | 192-1024 a.a. |
Description : | EIF2AK4 or eukaryotic translation initiation factor 2 alpha kinase 4 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 to downregulate protein synthesis in response to varied cellular stresses. The EIF2AK4 eIF2-alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid. |
Applications : | Kinase Assay; Western Blot |
Molecular Weight : | 132 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Form : | Recombinant protein stored in 50 mM Tris-HCl, ph 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol. |
Specific Activity : | 14 nmol/min/mg |
Purity : | > 95 % |
Concentration : | 0.1 ug/ul |
Sequences : | 192-1024 |
Storage : | Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Hepatitis C; Herpes simplex infection; Influenza A; Measles; Protein processing in endoplasmic reticulum |
Gene Name | EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 [ Homo sapiens ] |
Official Symbol | EIF2AK4 |
Synonyms | EIF2AK4; eukaryotic translation initiation factor 2 alpha kinase 4; GCN2; KIAA1338; eukaryotic translation initiation factor 2-alpha kinase 4; GCN2-like protein; GCN2 eIF2alpha kinase; NP_001013725.2; EC 2.7.11.1 |
Gene ID | 440275 |
mRNA Refseq | NM_001013703 |
Protein Refseq | NP_001013725 |
MIM | 609280 |
UniProt ID | Q9P2K8 |
Chromosome Location | 15q15.1 |
Function | ATP binding; aminoacyl-tRNA ligase activity; nucleotide binding; protein homodimerization activity; protein serine/threonine kinase activity |
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EIF2AK4-2700M | Recombinant Mouse EIF2AK4 Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF2AK4-3747HF | Active Recombinant Full Length Human EIF2AK4 Protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
EIF2AK4-6672HCL | Recombinant Human EIF2AK4 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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