Recombinant Human DVL2 Protein (Leu78-Thr250), His tagged

• Cat.No.: DVL2-2012H
• Product Overview: Recombinant human DVL2 (Leu78-Thr250) fused with His tag was expressed in E. coli.

Specification

• Description: Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 21.43 kDa
• Protein length: Leu78-Thr250
• Purity: >90% as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: DVL2 dishevelled, dsh homolog 2 (Drosophila) [ Homo sapiens (human) ]
• Official Symbol: DVL2
• Synonyms: DVL2; dishevelled, dsh homolog 2 (Drosophila); dishevelled 2 (homologous to Drosophila dsh); segment polarity protein dishevelled homolog DVL-2; DSH homolog 2; dishevelled-2
• Gene ID: 1856
• mRNA Refseq: NM_004422
• Protein Refseq: NP_004413
• MIM: 602151
• UniProt ID: O14641