Recombinant Human DST Protein, His-tagged

• Cat.No.: DST-688H
• Product Overview: Recombinant Human DST(Met1~Thr252) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 31.1kDa
• Protein length: Met1~Thr252
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: DST dystonin [ Homo sapiens ]
• Official Symbol: DST
• Synonyms: DST; dystonin; BPAG1, bullous pemphigoid antigen 1, 230/240kDa; bullous pemphigoid antigen 1; BP240; BPA; CATX 15; FLJ13425; FLJ21489; FLJ30627; FLJ32235; KIAA0728; MACF2; trabeculin-beta; dystonia musculorum protein; hemidesmosomal plaque protein; 230/240 kDa bullous pemphigoid antigen; bullous pemphigoid antigen 1, 230/240kDa; DT; DMH; BPAG1; CATX15; CATX-15; D6S1101; FLJ46791; KIAA0465; KIAA1470; DKFZp564B2416
• Gene ID: 667
• mRNA Refseq: NM_001723
• Protein Refseq: NP_001714
• MIM: 113810
• UniProt ID: Q03001