Recombinant Human Chemokine (C-X-C motif) Ligand 1 / Growth-regulated Alpha Protein, His-tagged

• Cat.No.: CXCL1-62H
• Product Overview: Recombinant human CXCL1 protein was expressed in E.coli and purified by using conventional chromatography techniques,10.1 kDa (94 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: CXCL1/GROa is a growth factor for melanoma cells and a chemotaxin for neutrophils. Similar to other alpha chemokines, this protein is potent neutrophil attractant and activator and is also active toward basophils. In addition, CXCL1 protein may be a therapeutic target as well as a diagnostic marker in ovarian cancer.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MASVATELRC QCLQTLQGIH PKNIQSVNVK SPGPHCAQTE VIATLKNGRK ACLNPASPIV KKIIEKMLNS DKSN
• Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
• Purity: > 90% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) [ Homo sapiens ]
• Synonyms: FSP; GRO; GRO-alpha(1-73); GRO1; GROA; MGSA; MGSA-a; NAP-3; SCYB1; C-X-C motif chemokine 1; GRO1 oncogene (melanoma growth stimulating activity, alpha) ; GRO1 oncogene (melanoma growth-stimulating activity) ; MGSA alpha; Melanoma growth stimulatory activity; Neutrophil-activating protein 3; chemokine (C-X-C motif) ligand 1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); fibroblast secretory protein; melanoma growth stimulatory activity alpha; CXCL1; Growth-regulated alpha protein
• Gene ID: 2919
• mRNA Refseq: NM_001511
• Protein Refseq: NP_001502
• MIM: 155730
• UniProt ID: P09341
• Chromosome Location: 4q21
• Pathway: Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Signaling by GPCR
• Function: chemokine activity; enzyme activator activity; growth factor activity