Recombinant Human CEL Protein, His/GST-tagged

• Cat.No.: CEL-569H
• Product Overview: Recombinant Human CEL(Asp117~Glu361) fused with His/GST tag at N-terminal was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 53.4kDa
• Protein length: Asp117~Glu361
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: CEL carboxyl ester lipase (bile salt-stimulated lipase) [ Homo sapiens ]
• Official Symbol: CEL
• Synonyms: CEL; carboxyl ester lipase (bile salt-stimulated lipase); bile salt-activated lipase; BSSL; MODY8; bucelipase; sterol esterase; cholesterol esterase; carboxyl ester hydrolase; bile-salt-activated lipase; pancreatic lysophospholipase; fetoacinar pancreatic protein; lysophospholipase, pancreatic; bile salt-dependent lipase, oncofetal isoform; BAL; FAP; BSDL; CELL; FAPP; LIPA; CEase
• Gene ID: 1056
• mRNA Refseq: NM_001807
• Protein Refseq: NP_001798
• MIM: 114840
• UniProt ID: P19835