Recombinant Human AP4B1 Protein, His-tagged

• Cat.No.: AP4B1-194H
• Product Overview: Recombinant Human AP4B1 Protein (Met1-Arg276) with N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 34.9 kDa
  Accurate Molecular Mass: 34 kDa
• Protein length: Met1-Arg276
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: AP4B1 adaptor-related protein complex 4, beta 1 subunit [ Homo sapiens (human) ]
• Official Symbol: AP4B1
• Synonyms: AP4B1; adaptor-related protein complex 4, beta 1 subunit; spastic paraplegia 47, SPG47; AP-4 complex subunit beta-1; beta 4 subunit of AP 4; BETA 4; beta4-adaptin; spastic paraplegia 47; beta 4 subunit of AP-4; CPSQ5; SPG47; BETA-4
• Gene ID: 10717
• mRNA Refseq: NM_001253852
• Protein Refseq: NP_001240781
• MIM: 607245
• UniProt ID: Q9Y6B7