AP4B1

  • Official Full Name

    adaptor-related protein complex 4, beta 1 subunit

  • Overview

    The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1) and epsilon-4 (AP4E1; MIM 607244), a medium chain, mu-4 (AP4M1; MIM 602296), and a small chain, sigma-4 (AP4S1; MIM 607243).

  • Synonyms

    AP4B1;adaptor-related protein complex 4, beta 1 subunit;AP-4 complex subunit beta-1;beta 4 subunit of AP 4;BETA 4;Adapter related protein complex 4 beta 1 subunit;AP 4 adapter complex subunit beta;AP 4 complex subunit beta 1;Beta subunit of AP 4;beta4-adaptin;OTTHUMP00000013725;OTTHUMP00000013726;OTTHUMP00000013730;beta subunit of AP-4;beta 4 subunit of AP-4;AP-4 adapter complex subunit beta;adapter-related protein complex 4 subunit beta-1;CPSQ5;BETA-4

Recombinant Proteins

  • Human
  • Zebrafish
  • Chicken
  • Mouse
  • E.coli
  • Mammalian Cells
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • GST
  • His
  • Non
Cat.# Product name Source (Host) Species Tag Protein Length Price
AP4B1-9725H Recombinant Human AP4B1, GST-tagged E.coli Human GST 1-351a.a.
AP4B1-10662Z Recombinant Zebrafish AP4B1 Mammalian Cells Zebrafish His
AP4B1-2606C Recombinant Chicken AP4B1 Mammalian Cells Chicken His
AP4B1-661H Recombinant Human AP4B1 protein, GST-tagged Wheat Germ Human GST
AP4B1-8806HCL Recombinant Human AP4B1 293 Cell Lysate HEK293 Human Non
AP4B1-1138HF Recombinant Full Length Human AP4B1 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 739 amino acids
AP4B1-194H Recombinant Human AP4B1 Protein, His-tagged E.coli Human His Met1-Arg276
Ap4b1-195M Recombinant Mouse Ap4b1 Protein, His-tagged E.coli Mouse His Met1-Ile261

    Involved Pathway

    AP4B1 involved in several pathways and played different roles in them. We selected most pathways AP4B1 participated on our site, such as Clathrin derived vesicle budding,Golgi Associated Vesicle Biogenesis,Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with AP4B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    trans-Golgi Network Vesicle Budding PUM1,TGOLN2,SNX9A,HIP1RB,SNX9,BLOC1S4,CPD,DTNBP1,CNO,YIPF6
    Vesicle-mediated transport PPP6R1,SEC22C,TFR1B,TRAPPC9,DNASE2,COPG,TRAPPC2L,STAB2,HYOU1,CLVS2
    Clathrin derived vesicle budding DNASE2,CLINT1,NECAP1,TPD52,SNAPIN,APPB,PLDN,APPA,AP3S1,PICALM
    Lysosome Vesicle Biogenesis DNASE2,AP1S3A,BLOC1S1,CLVS2,CTSZ,CLVS1
    Golgi Associated Vesicle Biogenesis TGOLN2,BLOC1S3,TFR1B,AP1S1,BLOC1S1,SH3D19,AP1B1,HIP1RB,AP3S1,SNX9
    Lysosome CTSBA,AGA,CLN3,CTSH,CD63,GALCA,ATP6V0D2,CTSM,SMPD1,GALC
    Membrane Trafficking PICALMB,MYO6B,PREB,CTSZ,HIP1R,EXOC6,GJB3,CLVS1,MIA3,TRAPPC1

    Protein Function

    AP4B1 has several biochemical functions, for example, protein binding,protein transporter activity,transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AP4B1 itself. We selected most functions AP4B1 had, and list some proteins which have the same functions with AP4B1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding FEN1,CPSF2,OAZ3,GUCY2C,PRAME,PDXP,TGFBI,SERPINB3C,ABCD1,SEMA6A
    protein transporter activity RUFY1,AP2B1,L7RN6,RANBP6,EIF4ENIF1,AP1S3B,KPNA7,PGAP2,CALCRL,CHMP7
    transporter activity ABCA1B,OCA2,SEC14L3,ATP5G1,HIAT1B,MIPB,SYPL2,FLR,AQP10A,FABP12

    Interacting Protein

    AP4B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AP4B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of AP4B1.

    ZNF576;FIBP;MYC;AP4E1;AP4S1

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