Recombinant Human ABL2, GST-tagged

• Cat.No.: ABL2-673H
• Product Overview: Recombinant Human ABL2 with a GST Tag at N-terminal is expressed inBaculovirus. MW=153 kDa.

Specification

• Cat. No.: ABL2-673H
• Description: Tyrosine-protein kinase ABL2 also known as Abelson-related gene protein (ABL2) is an enzyme that in humans is encoded by the ABL2 gene.ABL2 is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length.
• Source: Baculovirus.
• Purity: 63 %. The purity was assessed by SDS-PAGE/CBB staining.
• Buffer: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5.
• Storage And Handling: Store at -80℃. Avoid repeating freeze-thaws.

Gene Information

• Gene Name: ABL2 v-abl Abelson murine leukemia viral oncogene homolog 2 [ Homo sapiens ]
• Synonyms:
  ABL2; v-abl Abelson murine leukemia viral oncogene homolog 2; Abelson murine leukemia viral (v-abl) oncogene homolog 2; OTTHUMP00000033140; OTTHUMP00000218106; abelson murine leukemia viral oncogene homolog 2; abelson-related gene protein; arg tyrosine kinase; tyrosine-protein kinase ABL2; tyrosine-protein kinase ARG; v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene); ARG; ABLL; FLJ22224; FLJ31718; FLJ41441; ABL2; EC 2.7.10.2
• Gene ID: 27
• mRNA Refseq: NM_001136000
• Protein Refseq: NP_001129472
• MIM: 164690
• UniProt ID: P42684
• Chromosome Location: 1q24-q25
• Pathway: ErbB signaling pathway; Viral myocarditis
• Function: ATP binding; magnesium ion binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein tyrosine kinase activity; transferase activity