Recombinant Full Length Human LIMS1 Protein

• Cat.No.: LIMS1-284HF
• Product Overview: Recombinant full length Human LIMS1 with a N terminal proprietary tag; Predicted MWt 61.82 kDa.

Specification

• Description: The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 61.820kDa inclusive of tags
• Protein length: 325 amino acids
• AA Sequence: MANALASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQ CFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIG RVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRP CHNREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFN CANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPI EGRVVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYC ETHYNQLFGDVCFHCNRVIEGDVVSALNKAWCVNCFACST CNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLAE TLGRK
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: LIMS1 LIM and senescent cell antigen-like domains 1 [ Homo sapiens ]
• Official Symbol: LIMS1
• Synonyms: LIMS1; LIM and senescent cell antigen-like domains 1; LIM and senescent cell antigen-like-containing domain protein 1; PINCH; PINCH1
• Gene ID: 3987
• mRNA Refseq: NM_001193482
• Protein Refseq: NP_001180411
• MIM: 602567
• UniProt ID: P48059