Native Human Heparin Cofactor II

• Cat.No.: SERPIND1-12H
• Product Overview: Heparin Cofactor II is a single chain glycoprotein prepared from fresh frozen human plasma.

Specification

• Species: Human
• Source: Human Plasma
• Tag: Non
• Description: HCII is a specific inhibitor of thrombin with increased activity in the presence of heparin.
• Form: Frozen liquid
• Molecular Mass: 65,600
• Purity: >95% by SDS-PAGE analysis
• Usage: For in vitro laboratory use only
• Notes: Optimal experimental conditions and working dilutions must be determined by the end user. Sample concentration and volume are for example purposes only and do not necessarily represent the product that will be received. Please contact us for a current lot-specific product datasheet.
• Storage: -70°C
• Concentration: 5.0 mg/ml
• Storage Buffer: 0.02M Tris-HCl; 0.15M NaCl; 0.02% Sodium Azide; pH 7.4
• Preservative: SodiumAzide
• Shipping: Dry ice

Gene Information

• Gene Name: SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 [ Homo sapiens ]
• Official Symbol: SERPIND1
• Synonyms: SERPIND1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1; HCF2, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; heparin cofactor 2; D22S673; HC II; HC2; heparin cofactor II; HLS2; serpin D1; leuserpin 2; protease inhibitor leuserpin-2; serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; LS2; HCF2; HCII; THPH10
• Gene ID: 3053
• mRNA Refseq: NM_000185
• Protein Refseq: NP_000176
• MIM: 142360
• UniProt ID: P05546
• Chromosome Location: 22q11.21
• Pathway: Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem
• Function: endopeptidase inhibitor activity; heparin binding; serine-type endopeptidase inhibitor activity