Recombinant Human SERPIND1 Protein (Asp276-Ser499), His tagged

• Cat.No.: SERPIND1-5843H
• Product Overview: Recombinant human SERPIND1 (Asp276-Ser499) fused with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Asp276-Ser499
• Description: Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner.Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 26.33 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: SERPIND1 serpin family D member 1 [ Homo sapiens (human) ]
• Official Symbol: SERPIND1
• Synonyms: SERPIND1; serpin peptidase inhibitor, clade D (heparin cofactor), member 1; HCF2, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; heparin cofactor 2; D22S673; HC II; HC2; heparin cofactor II; HLS2; serpin D1; leuserpin 2; protease inhibitor leuserpin-2; serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1; LS2; HCF2; HCII; THPH10
• Gene ID: 3053
• mRNA Refseq: NM_000185
• Protein Refseq: NP_000176
• MIM: 142360
• UniProt ID: P05546