Native Human Fibronectin 1

• Cat.No.: FN1-700H
• Product Overview: Native Human FN1 was purified from Human foreskin fibroblasts.

Specification

• Species: Human
• Source: Human Foreskin Fibroblasts
• Tag: Non
• Description: This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.
• Molecular Mass: 560 kDa
• Purification: Affinity chromatography
• Storagebuffer: PBS pH 7.4
• Contents: 250 µg / 1 mg (1 mg / ml)
• Storage: - 20 °C. Repeated thawing and freezing must be avoided.
• OfficialSymbol: FN1

Gene Information

• Gene Name: FN1 fibronectin 1 [ Homo sapiens ]
• Synonyms: FN1; fibronectin 1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; fibronectin; cold-insoluble globulin; migration-stimulating factor
• Gene ID: 2335
• mRNA Refseq: NM_002026
• Protein Refseq: NP_002017
• MIM: 135600
• UniProt ID: P02751
• Chromosome Location: 2q34
• Pathway: ECM-receptor interaction; Focal adhesion; Pathways in cancer; Regulation of actin cytoskeleton; Hemostasis; Integrin cell surface interactions; Signaling in Immune system
• Function: collagen binding; extracellular matrix structural constituent; heparin binding