Active Recombinant Human TNFRSF6B protein(Met1-His300), hFc-tagged

Cat.No. : TNFRSF6B-432H
Product Overview : Recombinant Human TNFRSF6B protein(O95407)(Met1-His300), fused with C-terminal hFc tag, was expressed in Insect Cells.
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Species : Human
Source : Insect Cells
Tag : Fc
Protein Length : Met1-His300
similar : TNFRSF6B
Alias : TNFRSF6B; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; DcR3; DCR3; M68; TR6; decoy receptor 3; decoy receptor for Fas ligand; M68E; DJ583P15.1.1;
Conjugate : C-hFc
Form : Lyophilized from sterile 100mM Glycine, 10mM NaCl, pH 7.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Bioactivity : Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.5-3 μg/mL in the presence of 200 ng/mL recombinant human Fas ligand.
MolecularMass : The recombinant human DCR3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 508 amino acids and has a predicted molecular mass of 56.4 kDa. The apparent molecular mass of the protein is approximately 65 kDa in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 85 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
GeneName : TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens ]
GeneNameWeblink : 8771
OfficialSymbol : TNFRSF6B
OfficialSymbolWeblink : 8771
GeneID : 8771
GeneIDWeblink : 8771
mRNARefseq : NM_003823
mRNARefseqWeblink : NM_003823.3
ProteinRefseqWeblink : NP_003814.1
MIMWeblink : 603361
UniProtID : O95407
UniProtIDWeblink : O95407
Synonyms TNFRSF6B; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; DcR3; DCR3; M68; TR6; decoy receptor 3; decoy receptor for Fas ligand; M68E; DJ583P15.1.1;
MIM 603361

Not For Human Consumption!

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