Recombinant Human tumor necrosis factor receptor superfamily, member 6b, decoy, His-tagged

• Cat.No.: TNFRSF6B-333H
• Product Overview: TNFRSF6B, 30-300aa, Human, His tag, E.coli

Specification

• Description: TNFRSF6B belongs to Tumor necrosis factor receptor superfamily. It acts as a decoy receptor that competes with death receptors for ligand binding. This protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A. Recombinant human TNFRSF6B protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea
• Molecular Mass: 32.1 kDa(294aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSVAETPTY PWRDAETGER LVCAQCPPGT FVQRPCRRDS PTTCGPCPPR HYTQFWNYLE RCRYCNVLCG EREEEARACH ATHNRACRCR TGFFAHAGFC LEHASCPPGA GVIAPGTPSQ NTQCQPCPPG TFSASSSSSE QCQPHRNCTA LGLALNVPGS SSHDTLCTSC TGFPLSTRVP GAEECERAVI DFVAFQDISI KRLQRLLQAL EAPEGWGPTP RAGRAALQLK LRRRLTELLG AQDGALLVRL LQALRVARMP GLERSVRERF LPVH
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)
• Protein length: 30-300 a.a.

Gene Information

• Gene Name: TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens ]
• Official Symbol: TNFRSF6B
• Synonyms: TNFRSF6B; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; DcR3; DCR3; M68; TR6; decoy receptor 3; decoy receptor for Fas ligand; M68E; DJ583P15.1.1
• Gene ID: 8771
• mRNA Refseq: NM_003823
• Protein Refseq: NP_003814
• MIM: 603361
• UniProt ID: O95407
• Chromosome Location: 20q13.3
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: protein binding; receptor activity