Active Recombinant Human TNFRSF6B, Fc-tagged, Biotinylated

• Cat.No.: TNFRSF6B-595H
• Product Overview: The recombinant human DcR3-Fc fusion is expressed as a 499 amino acid protein consisting of Val30 - His300 region of DcR3 (UniProt accession #O95407) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions

Specification

• Source: Human cells
• Species: Human
• Tag: Fc
• Form: Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule)
• Bio-activity: Binds to human FasL and Light. Inhibits FasL--induced apoptosis in human Jurkat acute T cell leukemia cells.
• Molecular Mass: Calculated molecular mass (kDa): 53.3; Estimated by SDS-PAGE under reducing condition (kDa): ~60
• Endotoxin: <0.1 eu per 1 μg of purified recombinant protein determined by the
• Purity: >95% judged by SDS-PAGE under reducing condition
• Storage: The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles.
• Protein length: 30-300 a.a.

Gene Information

• Gene Name: TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens ]
• Official Symbol: TNFRSF6B
• Synonyms: TNFRSF6B; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; DcR3; DCR3; M68; TR6; decoy receptor 3; decoy receptor for Fas ligand; M68E; DJ583P15.1.1
• Gene ID: 8771
• mRNA Refseq: NM_003823
• Protein Refseq: NP_003814
• MIM: 603361
• UniProt ID: O95407
• Chromosome Location: 20q13.3
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: protein binding; receptor activity