Active Recombinant Human TNFRSF6B Protein, Fc Chimera

• Cat.No.: TNFRSF6B-1083H
• Product Overview: Recombinant Human TNFRSF6B (Accession # O95407), fused with , was produced in Spodoptera frugiperda, Sf 21 (baculovirus)-derived.

Specification

• Species: Human
• Source: Sf21 Cells
• Tag: Fc
• Predicted N Terminal: Val24
• Form: Lyophilized from a 0.2 µm filtered solution in MES and NaCl.
• Bio-activity: Measured by its ability to inhibit Fas Ligand-induced apoptosis of Jurkat human acute T cell leukemia cells. Cheng, J. et al. (1994) Science 263:1759.The ED50 for this effect is typically 0.03 - 0.15 µg/mL in the presence of 20 ng/mL rhFas Ligand.
• Molecular Mass: Recombinant Human TNFRSF6B, Fc Chimera has a calculated MW of 57 kDa (monomer). In SDS-PAGE migrates as 60-65 kDa, reducing conditions.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens ]
• Official Symbol: TNFRSF6B
• Synonyms: TNFRSF6B; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; DcR3; DCR3; M68; TR6; decoy receptor 3; decoy receptor for Fas ligand; M68E; DJ583P15.1.1
• Gene ID: 8771
• mRNA Refseq: NM_003823
• Protein Refseq: NP_003814
• MIM: 603361
• UniProt ID: O95407
• Chromosome Location: 20q13.3