Active Recombinant Human IL27RA, HIgG1 Fc-tagged
| Cat.No. : | IL27RA-783H |
| Product Overview : | The extracellular domain of human IL-27RA (AAH28003.1) (Gly34-Lys516) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell. |
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| Description : | IL27RA (interleukin 27 receptor, alpha) is a protein-coding gene. Diseases associated with IL27RA include membranous glomerulonephritis, and glomerulonephritis, and among its related super-pathways are Th1 Differentiation. GO annotations related to this gene include transmembrane signaling receptor activity and interleukin-27 receptor activity. |
| Source : | CHO cell |
| Species : | Human |
| Tag : | HIgG1 Fc-tagged |
| Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
| Bio-activity : | Measured by its ability to inhibit IL-27-induced proliferation of mouse CD4+ T cells. |
| Molecular Mass : | 78KDa (monomer) |
| AA Sequence : | Gly34-Lys516 |
| Endotoxin : | <0.06 eu/μg="" as="" determined="" by="" lal="" test.=""> |
| Purity : | >98%, by SDS-PAGE under reducing conditions. |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
| Warning : | Avoid freeze/thaw cycles. |
| Protein length : | 34-516 a.a. |
| Gene Name | IL27RA interleukin 27 receptor, alpha [ Homo sapiens ] |
| Official Symbol | IL27RA |
| Synonyms | IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; CRL1; IL 27R; T cell cytokine receptor type 1; TCCR; WSX 1; WSX1; zcytor1; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; cytokine receptor-like 1; class I cytokine receptor; IL-27 receptor subunit alpha; T-cell cytokine receptor type 1; type I T-cell cytokine receptor; IL27R; |
| Gene ID | 9466 |
| mRNA Refseq | NM_004843 |
| Protein Refseq | NP_004834 |
| MIM | 605350 |
| UniProt ID | Q6UWB1 |
| Chromosome Location | 19p13.11 |
| Pathway | IL27-mediated signaling events, organism-specific biosystem; |
| Function | interleukin-27 receptor activity; receptor activity; transmembrane signaling receptor activity; |
Not For Human Consumption!
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