IL27RA
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Official Full Name
interleukin 27 receptor, alpha -
Overview
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. -
Synonyms
IL27RA;interleukin 27 receptor, alpha;interleukin-27 receptor subunit alpha;CRL1;IL 27R;T cell cytokine receptor type 1;TCCR;WSX 1;WSX1;zcytor1;IL-27RA;IL-27R-alpha;IL-27R subunit alpha;cytokine receptor-like 1;class I cytokine receptor;IL-
Recombinant Proteins
- Mouse
- Human
- Rat
- Mus musculus
- Mammalian cells
- CHO
- C-His
- HEK293
- E.coli
- Mammalian Cell
- Human Cell
- Human Cells
- HEK293T
- Wheat Germ
- E.coli expression system
- Fc
- His
- His&T7
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
- GST
Involved Pathway
IL27RA involved in several pathways and played different roles in them. We selected most pathways IL27RA participated on our site, such as Jak-STAT signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL27RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Jak-STAT signaling pathway | AOX2P,SOCS4,IFNA6,PIM1,CCND2A,LIF,CCND2,CSF3,PIK3R2,HRAS |
Protein Function
IL27RA has several biochemical functions, for example, interleukin-27 receptor activity,transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL27RA itself. We selected most functions IL27RA had, and list some proteins which have the same functions with IL27RA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transmembrane signaling receptor activity | PTH1RA,NRXN1,GPR124,CD3D,TLR5,CD79B,TLR2-1,TNFRSF10C,IL4R.1,CLEC2H |
| interleukin-27 receptor activity | IL6ST |
Interacting Protein
IL27RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL27RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL27RA.
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