Active Recombinant Human Il27RA, MIgG2a Fc-tagged

• Cat.No.: Il27RA-782H
• Product Overview: The extracellular domain of human IL-27RA (AAH28003.1) (Gly34-Lys516) is fused to the N-terminus of the Fc region of mouse IgG2awas expressed in CHO cell

Specification

• Species: Human
• Source: CHO
• Tag: Fc
• Protein Length: 34-516 a.a.
• Description: IL27RA (interleukin 27 receptor, alpha) is a protein-coding gene. Diseases associated with IL27RA include membranous glomerulonephritis, and glomerulonephritis, and among its related super-pathways are Th1 Differentiation. GO annotations related to this gene include transmembrane signaling receptor activity and interleukin-27 receptor activity.
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by its ability to inhibit IL-27-induced proliferation of mouse CD4+ T cells.
• Molecular Mass: 78KDa (monomer)
• AA Sequence: Gly34-Lys516
• Endotoxin: <0.06 eu/μg="" as="" determined="" by="" lal="" test.="">
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: IL27RA interleukin 27 receptor, alpha [ Homo sapiens ]
• Official Symbol: IL27RA
• Synonyms: IL27RA; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; CRL1; IL 27R; T cell cytokine receptor type 1; TCCR; WSX 1; WSX1; zcytor1; IL-27RA; IL-27R-alpha; IL-27R subunit alpha; cytokine receptor-like 1; class I cytokine receptor; IL-27 receptor subunit alpha; T-cell cytokine receptor type 1; type I T-cell cytokine receptor; IL27R
• Gene ID: 9466
• mRNA Refseq: NM_004843
• Protein Refseq: NP_004834
• MIM: 605350
• UniProt ID: Q6UWB1
• Chromosome Location: 19p13.11
• Pathway: IL27-mediated signaling events, organism-specific biosystem
• Function: interleukin-27 receptor activity; receptor activity; transmembrane signaling receptor activity