APOC3
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Official Full Name
apolipoprotein C-III -
Overview
Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. It inhibits lipoprotein lipase and hepatic lipase and it is thought to delay catabolism of triglyceride-rich particles. An increase in apoC-III levels induces the development of hypertriglyceridemia. -
Synonyms
APOC3;apolipoprotein C-III;APOCIII;MGC150353;apo-CIII;apoC-III;apolipoprotein C3;OTTHUMP00000043270;OTTHUMP00000069353
Recombinant Proteins
- Mouse
- Rat
- Human
- Chicken
- Cynomolgus
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- Yeast
- Insect Cell
- Human Plasma
- Mamanlian cells
- HEK293T
- Human plasma
- His&SUMO
- His
- Myc&DDK
- His&GST
- GST
- Non
- SUMO
- His&MBP
- Flag
- His&Fc&Avi
Involved Pathway
APOC3 involved in several pathways and played different roles in them. We selected most pathways APOC3 participated on our site, such as PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with APOC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PPAR signaling pathway | FABP7B,SCD5,RXRGA,ACSL4B,ME1,ILK,RXRB,FABP3,APOA2,ACSL1A |
Protein Function
APOC3 has several biochemical functions, for example, cholesterol binding,enzyme regulator activity,high-density lipoprotein particle receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by APOC3 itself. We selected most functions APOC3 had, and list some proteins which have the same functions with APOC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cholesterol binding | TSPO,ERLIN2,ERLIN1,PTCH1,PROM2,STARD6,OSBPL7,CAV1,STARD3,NR1H3 |
| enzyme regulator activity | RGN,PSMD3,BRCC3,CPN2,EIF2B1,PPP1R7,PSMD1,PSMD2,DPM2,MTMR9 |
| high-density lipoprotein particle receptor binding | APOA2,APOA1 |
| phospholipid binding | ABCG1,APOH,SPTBN1,PLA2G2A,DAPP1,LRBA,MTAP1B,PACSIN1A,NBEAL2,CPS1 |
| lipase inhibitor activity | APOC1,APOC2,APOA1,FAF2,APOA2 |
Interacting Protein
APOC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with APOC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of APOC3.
ARFGAP1;d-mannose;APOA1;ALB
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