Recombinant Rat Calr Protein, His-tagged

• Cat.No.: Calr-357R
• Product Overview: Recombinant Rat Calr Protein (Ala72-Lys322) with N-His tag was expressed in E. coli.

Specification

• Description: Enables several functions, including hormone binding activity; metal ion binding activity; and peptide binding activity. Involved in several processes, including cellular response to lithium ion; response to estradiol; and response to testosterone. Located in several cellular components, including acrosomal vesicle; endoplasmic reticulum; and perinuclear region of cytoplasm. Part of protein-containing complex. Biomarker of vitamin B12 deficiency. Human ortholog(s) of this gene implicated in essential thrombocythemia; myelofibrosis; pancreatic ductal adenocarcinoma; sideroblastic anemia; and thrombocytosis. Orthologous to human CALR (calreticulin).
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29 kDa
  Accurate Molecular Mass: 38 kDa
• Protein length: Ala72-Lys322
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Calr calreticulin [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Calr
• Synonyms: CALR; calreticulin; CABP3; CALBP; CRP55; ERp60; HACBP; calregulin; calcium-binding protein 3; endoplasmic reticulum resident protein 60
• Gene ID: 64202
• mRNA Refseq: NM_022399
• Protein Refseq: NP_071794
• UniProt ID: P18418