Recombinant Rat Anxa2 Protein, His-tagged

• Cat.No.: Anxa2-165R
• Product Overview: Recombinant Rat Anxa2 Protein (Asn41-Asp182) with N-His tag was expressed in E. coli.

Specification

• Description: Enables bone sialoprotein binding activity; phosphatidylinositol-4,5-bisphosphate binding activity; and small GTPase binding activity. Involved in several processes, including positive regulation of fibroblast proliferation; protein localization to plasma membrane; and response to thyroid hormone. Located in several cellular components, including macropinosome; membrane raft; and ruffle. Part of protein-containing complex. Biomarker of hyperthyroidism; hypothyroidism; and renal cell carcinoma. Human ortholog(s) of this gene implicated in osteonecrosis. Orthologous to several human genes including ANXA2 (annexin A2).
• Source: E. coli
• Species: Rat
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 17.4 kDa
• Protein length: Asn41-Asp182
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Anxa2 annexin A2 [ Rattus norvegicus (Norway rat) ]
• Official Symbol: Anxa2
• Synonyms: ANXA2; annexin A2; p36; PAP-IV; annexin-2; protein I; lipocortin II; chromobindin-8; calpactin I heavy chain; calpactin-1 heavy chain; placental anticoagulant protein IV; ANX2
• Gene ID: 56611
• mRNA Refseq: NM_019905
• Protein Refseq: NP_063970
• UniProt ID: Q07936