Recombinant Mouse Xpnpep3 Protein, Myc/DDK-tagged

• Cat.No.: Xpnpep3-7020M
• Product Overview: Purified recombinant protein of Mouse X-prolyl aminopeptidase 3, mitochondrial (Xpnpep3), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala. Also shows low activity towards peptides with Ala or Ser at the P1 position. Promotes TNFRSF1B-mediated phosphorylation of MAPK8/JNK1 and MAPK9/JNK2, suggesting a function as an adapter protein for TNFRSF1B; the effect is independent of XPNPEP3 peptidase activity. May inhibit apoptotic cell death induced via TNF-TNFRSF1B signaling.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 43.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Xpnpep3 X-prolyl aminopeptidase 3, mitochondrial [ Mus musculus (house mouse) ]
• Official Symbol: Xpnpep3
• Synonyms: XPNPEP3; X-prolyl aminopeptidase (aminopeptidase P) 3, putative; probable Xaa-Pro aminopeptidase 3; aminopeptidase P3; X-Pro aminopeptidase 3; APP3; E430012M05Rik
• Gene ID: 321003
• mRNA Refseq: NM_177310
• Protein Refseq: NP_796284
• UniProt ID: B7ZMP1