Recombinant Mouse Snrpc Protein, Myc/DDK-tagged

• Cat.No.: Snrpc-6006M
• Product Overview: Purified recombinant protein of mouse full-length U1 small nuclear ribonucleoprotein C (Snrpc), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 17.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Snrpc U1 small nuclear ribonucleoprotein C [ Mus musculus (house mouse) ]
• Official Symbol: Snrpc
• Synonyms: SNRPC; U1 small nuclear ribonucleoprotein C; U1 snRNP C; U1 snRNP protein C; U1 small nuclear ribonucleoprotein 1C; U1C; U1-C; Snrp1c
• Gene ID: 20630
• mRNA Refseq: NM_011432
• Protein Refseq: NP_035562
• UniProt ID: Q62241