Recombinant Mouse Rorc Protein, His-tagged

• Cat.No.: Rorc-2027M
• Product Overview: Recombinant Mouse Rorc Protein (Asp267-Lys516) with N-His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Asp267-Lys516
• Description: Enables DNA-binding transcription factor activity, RNA polymerase II-specific and transcription coactivator binding activity. Involved in several processes, including hematopoietic or lymphoid organ development; negative regulation of thymocyte apoptotic process; and regulation of gene expression. Acts upstream of or within hematopoietic or lymphoid organ development; protein phosphorylation; and regulation of gamma-delta T cell differentiation. Located in external side of plasma membrane and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system; sensory organ; and thyroid gland. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in immunodeficiency 42. Orthologous to human RORC (RAR related orphan receptor C).
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 32.7 kDa
  Accurate Molecular Mass: 33 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Rorc RAR-related orphan receptor gamma [ Mus musculus (house mouse) ]
• Official Symbol: Rorc
• Synonyms: Rorc; RAR-related orphan receptor gamma; TOR; Thor; Nr1f3; RORgamma; nuclear receptor ROR-gamma; RAR-related orphan receptor C; nuclear receptor RZR-gamma; nuclear receptor subfamily 1 group F member 3; retinoid-related orphan receptor-gamma; thymus orphan receptor
• Gene ID: 19885
• mRNA Refseq: NM_011281
• Protein Refseq: NP_035411
• UniProt ID: P51450