Recombinant Mouse Ptpra Protein, Myc/DDK-tagged

• Cat.No.: Ptpra-5243M
• Product Overview: Purified recombinant protein of mouse full-length protein tyrosine phosphatase, receptor type, A (Ptpra), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Tyrosine protein phosphatase which is involved in integrin-mediated focal adhesion formation. Following integrin engagement, specifically recruits BCAR3, BCAR1 and CRK to focal adhesions thereby promoting SRC-mediated phosphorylation of BRAC1 and the subsequent activation of PAK and small GTPase RAC1 and CDC42.
• Molecular Mass: 94.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ptpra protein tyrosine phosphatase, receptor type, A [ Mus musculus (house mouse) ]
• Official Symbol: Ptpra
• Synonyms: PTPRA; protein tyrosine phosphatase, receptor type, A; receptor-type tyrosine-protein phosphatase alpha; PTPTY-28; R-PTP-alpha; LCA-related phosphatase; protein-tyrosine phosphatase alpha; Ptpa; Rptra; Ptpalpha; Rptpalpha; Rptralpha; MGC118095
• Gene ID: 19262
• mRNA Refseq: NM_008980
• Protein Refseq: NP_033006
• UniProt ID: P18052