Recombinant Human PTPRA, GST-tagged, Active

• Cat.No.: PTPRA-467H
• Product Overview: Recombinant human PTPRA (174-802) was expressed bybaculovirusinSf9 insect cellsusing an N-terminal GST tag. MW=96 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 174-802 a.a.
• Description: PTPRA (also known as LRP) is a member of the protein tyrosine phosphatase family and contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. PTPRA dephosphorylates SRC family kinases, potassium channels and NMDA receptors and exists as three alternatively spliced variants which encode two distinct isoforms. Absence of PTPRA compromises correct positioning of pyramidal neurons during development of mouse hippocampus.
• Sequence: 174-802.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• 22q13.33: 20p13

Gene Information

• Gene Name: PTPRA protein tyrosine phosphatase, receptor type, A [ Homo sapiens ]
• Synonyms: PTPRA; protein tyrosine phosphatase, receptor type, A; Leukocyte common antigen-related peptide (protein tyrosine phosphate); OTTHUMP00000030064; PTPLCA-related phosphatase; PTPase-alpha; protein tyrosine phosphatase, receptor type, alpha polypeptide; tyrosine phosphatase alpha; LRP; HLPR; PTPA; HEPTP; HPTPA; RPTPA; PTPRL2; HPTPalpha; R-PTP-alpha; EC 3.1.3.48
• Gene ID: 5786
• mRNA Refseq: NM_002836
• Protein Refseq: NP_002827
• MIM: 176884
• UniProt ID: P18433
• Pathway: Axon guidance
• Function: hydrolase activity; transmembrane receptor protein tyrosine phosphatase activity