Recombinant Mouse Ptpn12 Protein, Myc/DDK-tagged

• Cat.No.: Ptpn12-5236M
• Product Overview: Purified recombinant protein of mouse full-length protein tyrosine phosphatase, non-receptor type 12 (Ptpn12), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2. Selectively dephosphorylates ERBB2 phosphorylated at 'Tyr-1112', 'Tyr-1196', and/or 'Tyr-1248'.
• Molecular Mass: 87 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ptpn12 protein tyrosine phosphatase, non-receptor type 12 [ Mus musculus (house mouse) ]
• Official Symbol: Ptpn12
• Synonyms: PTPN12; protein tyrosine phosphatase, non-receptor type 12; tyrosine-protein phosphatase non-receptor type 12; MPTP-PEST; protein-tyrosine phosphatase P19; PTPG1; P19-PTP; PTP-P19; PTP-PEST
• Gene ID: 19248
• mRNA Refseq: NM_011203
• Protein Refseq: NP_035333
• UniProt ID: P35831