Recombinant Mouse Psmc3ip Protein, Myc/DDK-tagged

• Cat.No.: Psmc3ip-5185M
• Product Overview: Purified recombinant protein of mouse full-length proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein (Psmc3ip), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Plays an important role in meiotic recombination. Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
• Molecular Mass: 24.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Psmc3ip proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein [ Mus musculus (house mouse) ]
• Official Symbol: Psmc3ip
• Synonyms: PSMC3IP; proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein; homologous-pairing protein 2 homolog; PSMC3-interacting protein; TBP-1-interacting protein; tat-binding protein 1-interacting protein; proteasome 26S ATPase subunit 3-interacting protein; HOP2; GT198; Tbpip; C79099
• Gene ID: 19183
• mRNA Refseq: NM_008949
• Protein Refseq: NP_032975
• UniProt ID: O35047