Recombinant Human PSMC3IP Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PSMC3IP-4450H
• Product Overview: PSMC3IP MS Standard C13 and N15-labeled recombinant protein (NP_037422) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants.
• Molecular Mass: 23.6 kDa
• AA Sequence: MSKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKIKEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRYMEAEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKYCKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PSMC3IP PSMC3 interacting protein [ Homo sapiens (human) ]
• Official Symbol: PSMC3IP
• Synonyms: PSMC3IP; PSMC3 interacting protein; homologous-pairing protein 2 homolog; GT198; HUMGT198A; TBP 1 interacting protein; TBPIP; DBD-interacting; TBP-1-interacting protein; nuclear receptor coactivator GT198; tat-binding protein 1-interacting protein; proteasome 26S ATPase subunit 3-interacting protein; HOP2; ODG3
• Gene ID: 29893
• mRNA Refseq: NM_013290
• Protein Refseq: NP_037422
• MIM: 608665
• UniProt ID: Q9P2W1