Recombinant Mouse Prion Protein, Globular Domain, His-tagged

• Cat.No.: Prnp-1064M

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Description: N-terminal His-tagged full-length prion protein (PrPc). The PrPc -like conformation of the protein after refolding procedure was confirmed by high resolution NMR spectroscopy. The native His tagged PrPc is the ideal tool for in vitro/in vivo investigations of the behaviour of cellular prions. It may be used for protein-protein interaction studies as well as for in vitro/in vivo conversion studies.
• Form: Liquid.Supplied in 10 mM sodium acetate pH 4.5 and 0.02 % sodium azide.
• Purity: >95% by SDS-PAGE.
• Usage: For in vitro use only.
• Storage: Quality guaranteed for 12 months store at - 80°C. Avoid freeze / thaw cycles.

Gene Information

• Gene Name: Prnp prion protein [ Mus musculus ]
• Synonyms: Prnp; prion protein; PrP; PrPC; Sinc; CD230; PrPSc; Prn-i; Prn-p; PrP<C>; AA960666; AI325101; OTTMUSP00000015760
• Gene ID: 19122
• mRNA Refseq: NM_011170
• Protein Refseq: NP_035300
• UniProt ID: P04925
• Chromosome Location: 2 75.0 cM
• Pathway: Prion diseases
• Function: copper ion binding