Recombinant Mouse Pcbp2 Protein, Myc/DDK-tagged

• Cat.No.: Pcbp2-4697M
• Product Overview: Purified recombinant protein of mouse full-length poly(rC) binding protein 2 (Pcbp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation.
• Molecular Mass: 38.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Pcbp2 poly(rC) binding protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Pcbp2
• Synonyms: PCBP2; poly(rC) binding protein 2; poly(rC)-binding protein 2; CBP; CTBP; hnRNP X; alpha-CP2; heterogeneous nuclear ribonucleoprotein X; putative heterogeneous nuclear ribonucleoprotein X; Hnrpx; AW412548; alphaCP-2; MGC107004
• Gene ID: 18521
• mRNA Refseq: NM_001103165
• Protein Refseq: NP_001096635
• UniProt ID: Q61990