Recombinant Mouse Park7 Protein, His-tagged

• Cat.No.: Park7-1900M
• Product Overview: Recombinant Mouse Park7 Protein (Ala2-Asp189) with N-His tag was expressed in E. coli.

Specification

• Description: Enables oxygen sensor activity and peroxiredoxin activity. Involved in several processes, including detoxification of inorganic compound; negative regulation of intrinsic apoptotic signaling pathway; and negative regulation of protein metabolic process. Acts upstream of or within several processes, including dopamine uptake involved in synaptic transmission; membrane hyperpolarization; and positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway. Located in several cellular components, including cell body; endoplasmic reticulum; and mitochondrion. Is expressed in central nervous system and retina. Used to study Parkinson's disease 7. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinson's disease 7; Parkinsonism; cerebral infarction; and middle cerebral artery infarction. Orthologous to human PARK7 (Parkinsonism associated deglycase).
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 23.5 kDa
  Accurate Molecular Mass: 24 kDa
• Protein length: Ala2-Asp189
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: Park7 Parkinson disease (autosomal recessive, early onset) 7 [ Mus musculus (house mouse) ]
• Official Symbol: Park7
• Synonyms: PARK7; Parkinson disease (autosomal recessive, early onset) 7; protein DJ-1; parkinson disease protein 7 homolog; RNA-binding protein regulatory subunit; Dj1; DJ-1
• Gene ID: 57320
• mRNA Refseq: NM_020569
• Protein Refseq: NP_065594
• UniProt ID: Q99LX0