Recombinant Mouse Park7 protein, His-tagged

• Cat.No.: Park7-34M
• Product Overview: Recombinant mouse Park7, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: Park7 also known as protein DJ-1 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. Play an important role in cell protection against oxidative stress and cell death acting as oxidative stress sensor and redox-sensitive chaperone and protease.
• Source: E. coli
• Species: Mouse
• Tag: His
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 20% glycerol, 1mM DTT
• Molecular Mass: 22.4 kDa (212aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMASKRAL VILAKGAEEM ETVIPVDVMR RAGIKVTVAG LAGKDPVQCS RDVMICPDTS LEDAKTQGPY DVVVLPGGNL GAQNLSESPM VKEILKEQES RKGLIAAICA GPTALLAHEV GFGCKVTTHP LAKDKMMNGS HYSYSESRVE KDGLILTSRG PGTSFEFALA IVEALVGKDM ANQVKAPLVL KD
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: Park7 Parkinson disease (autosomal recessive, early onset) 7 [ Mus musculus ]
• Official Symbol: Park7
• Synonyms: PARK7; Parkinson disease (autosomal recessive, early onset) 7; protein DJ-1; parkinson disease protein 7 homolog; RNA-binding protein regulatory subunit; Dj1; DJ-1
• Gene ID: 57320
• mRNA Refseq: NM_020569
• Protein Refseq: NP_065594
• Pathway: Parkinsons disease, organism-specific biosystem; mRNA processing, organism-specific biosystem
• Function: RNA binding; hydrolase activity; mRNA binding; peptidase activity; peroxidase activity; peroxiredoxin activity; protein homodimerization activity