Recombinant Mouse Ophn1 Protein, Myc/DDK-tagged

• Cat.No.: Ophn1-4594M
• Product Overview: Purified recombinant protein of mouse full-length oligophrenin 1 (Ophn1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals. Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation.
• Molecular Mass: 92.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Ophn1 oligophrenin 1 [ Mus musculus (house mouse) ]
• Official Symbol: Ophn1
• Synonyms: OPHN1; oligophrenin 1; oligophrenin-1; MGC6513; C130037N19Rik
• Gene ID: 94190
• mRNA Refseq: NM_052976
• Protein Refseq: NP_443208
• UniProt ID: Q99J31