Recombinant Mouse Numb Protein, Myc/DDK-tagged

• Cat.No.: Numb-4547M
• Product Overview: Purified recombinant protein of mouse full-length NUMB endocytic adaptor protein (Numb), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a conserved protein that is distributed asymmetrically during cell division in the developing embryo. The encoded protein participates in cell fate decisions by interacting with the Notch receptor. Loss of function of this gene results in severe defects in neural development and loss of viability. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 71.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Numb NUMB endocytic adaptor protein [ Mus musculus (house mouse) ]
• Official Symbol: Numb
• Synonyms: NUMB; numb gene homolog (Drosophila); protein numb homolog; mnb; m-Nb; m-numb
• Gene ID: 18222
• mRNA Refseq: NM_001136075
• Protein Refseq: NP_001129547
• UniProt ID: Q9QZS3