Recombinant Mouse Lefty1 Protein, His/GST-tagged

• Cat.No.: Lefty1-370M
• Product Overview: Recombinant Mouse Lefty1(Ser169~Pro368) fused with His/GST tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. Mice lacking a functional copy of this gene exhibit embryonic lethality and defects in left-right patterning.
• Source: E. coli
• Species: Mouse
• Tag: His&GST
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 49.3kDa
• Protein length: Ser169~Pro368
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: Lefty1 left right determination factor 1 [ Mus musculus ]
• Official Symbol: Lefty1
• Synonyms: LEFTY1; left right determination factor 1; left-right determination factor 1; TGF-beta-4; protein lefty-1; transforming growth factor beta-4; left-right determination, factor B; stimulated by retinoic acid gene 3 protein; Ebaf; Leftb; Stra3; Tgfb4; lefty; lefty-1; AI450052
• Gene ID: 13590
• mRNA Refseq: NM_010094
• Protein Refseq: NP_034224
• UniProt ID: Q64280