Recombinant Mouse Kremen2 Protein, Myc/DDK-tagged

• Cat.No.: Kremen2-3732M
• Product Overview: Purified recombinant protein of mouse full-length kringle containing transmembrane protein 2 (Kremen2), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: Myc&DDK
• Description: Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning and can also negatively regulate bone formation.
• Molecular Mass: 49.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Kremen2 kringle containing transmembrane protein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Kremen2
• Synonyms: KREMEN2; kringle containing transmembrane protein 2; kremen protein 2; dickkopf receptor 2; kringle domain-containing transmembrane protein 2; kringle-containing protein marking the eye and the nose; Krm2; 2900054E04Rik
• Gene ID: 73016
• mRNA Refseq: NM_028416
• Protein Refseq: NP_082692
• UniProt ID: Q8K1S7