Recombinant Mouse Interferon Alpha 1

• Cat.No.: Ifna1-141M
• Product Overview: Recombinant human Ifna1was expressed in E. coli.

Specification

• Cat. No.: Ifna1-141M
• Description: Ifna1 is aprotein that in humans is encoded by the IFNA1 gene. Leukocyte interferon isproduced predominantly by B lymphocytes. Immune interferon (IFN-gamma; MIM147570) is produced by mitogen- or antigen-stimulated T lymphocytes.
• Source: E. coli
• Species: Human
• Form: Liquid in PBS + 0.1%BSA.
• Molecular Weight: 19.323 kDa
• Concentration: 1 x 106units/ml
• Purity: 95%
• Biological Activity: Ifna1 wastitrated with the use of the cytopathic effect inhibition assay. In this antiviralassay for interferon, about 1 unit/ml of interferon is the quantity necessarytoproducea cytopathic effect of 50%. The units are determined with respect to the Ifna1reference standard for mouse interferon alpha (mouse IFN- ) provided by theNational Institutes of Health. Unit of activity measured on mouse L929 cellswithencephalomyocarditisvirus (EMCV).
• Storage: Store at-80°C. Dilute only in buffers containing protein such as 0.1% BSA. Pleasenotethatthe addition of any carrier protein into this product may produce unwanted endotoxin.This depends upon the particular application employed. Avoid repeatedfreeze-thaw cycles.
• OfficialSymbol: Ifna1
• Tag: Non

Gene Information

• Gene Name: Ifna1 interferon alpha 1 [ Musmusculus ]
• Synonyms: Ifna1; interferonalpha 1; Ifa1;interferon alpha-1; IFN-alpha-1; OTTMUSP00000008138; interferon alpha familygene 1
• Gene ID: 15962
• mRNA Refseq: NM_010502
• Protein Refseq: NP_034632
• Chromosome Location: 4 C4; 442.6 cM
• Pathway: Autoimmune thyroiddisease; Cytokine-cytokine receptor interaction; Cytokines and InflammatoryResponse (BioCarta); Cytosolic DNA-sensing pathway; Hepatitis C; Herpessimplex infection; IL-2 Signaling Pathway; Influenza A; Jak-STAT signalingpathway; Measles; Natural killer cell mediated cytotoxicity; RIG-I-likereceptor signaling pathway; Regulation of autophagy; Toll-like receptorsignaling pathway; Tuberculosis
• Function: cytokine activity; cytokinereceptor binding