Recombinant Mouse Il12rb1 Protein, MYC/DDK-tagged

• Cat.No.: Il12rb1-1238M
• Product Overview: Purified recombinant protein of full-length mouse interleukin 12 receptor, beta 1 (Il12rb1), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
• Molecular Mass: 82.2 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Il12rb1 interleukin 12 receptor, beta 1 [ Mus musculus (house mouse) ]
• Official Symbol: Il12rb1
• Synonyms: Il12rb1; interleukin 12 receptor, beta 1; CD212; IL-12R[b]; interleukin-12 receptor subunit beta-1; IL-12 receptor beta component; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component)
• Gene ID: 16161
• mRNA Refseq: NM_008353
• Protein Refseq: NP_032379
• UniProt ID: Q60837