Recombinant mouse Ighg, His-tagged

• Cat.No.: Ighg-15852M
• Product Overview: Recombinant mouse IgG protein, fused to His tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.

Specification

• Species: Mouse
• Source: Hi-5 Insect Cells
• Tag: His
• Protein Length: 98-330aa
• Description: Immunoglobulin G (IgG) is antibody molecules. Each IgG is composed of four peptide chains — two heavy chains gamma and two light chains. Each IgG has two antigen binding sites. IgG antibodies are involved in predominantly the secondary immune response. The presence of specific IgG, in general, corresponds to maturation of the antibody response. It also plays an important role in Antibody-dependent cell-mediated cytotoxicity(ADCC) and Intracellular antibody-mediated proteolysis, in which it binds to TRIM21 (the receptor with greatest affinity to IgG in humans) in order to direct marked virions to the proteasome in the cytosol.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol
• Molecular Mass: 27.5kDa (242aa)
• AA Sequence: ADPEPRGPTI KPCPPCKCPA PNLLGGPSVF IFPPKIKDVL MISLSPIVTC VVVDVSEDDP DVQISWFVNN VEVHTAQTQT HREDYNSTLR VVSALPIQHQ DWMSGKEFKC KVNNKDLPAP IERTISKPKG SVRAPQVYVL PPPEEEMTKK QVTLTCMVTD FMPEDIYVEW TNNGKTELNYKNTEPVLDSD GSYFMYSKLR VEKKNWVERN SYSCSVVHEG LHNHHTTKSF SRTPGKHHHH HH
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: Ighg Immunoglobulin heavy chain (gamma polypeptide) [ Mus musculus (house mouse) ]
• Official Symbol: Ighg
• Synonyms: Ighg; Immunoglobulin heavy chain (gamma polypeptide); IGHG2A; AU044919
• Gene ID: 380794
• Chromosome Location: 12 F2; 12