Recombinant Mouse Dmc1 Protein, Myc/DDK-tagged

• Cat.No.: Dmc1-2583M
• Product Overview: Purified recombinant protein of mouse full-length DNA meiotic recombinase 1 (Dmc1), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. In mouse, deficiency of this gene causes infertility. Alternative splicing results in multiple transcript variants.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 37.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Dmc1 DNA meiotic recombinase 1 [ Mus musculus (house mouse) ]
• Official Symbol: Dmc1
• Synonyms: DMC1; DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast); meiotic recombination protein DMC1/LIM15 homolog; disrupted meiotic cDNA 1 homolog; sgdp; Dmc1h; Mei11; MGC151144
• Gene ID: 13404
• mRNA Refseq: NM_010059
• Protein Refseq: NP_034189
• UniProt ID: Q61880